Therapeutic Complement Targeting in ANCA-Associated Vasculitides and Thrombotic Microangiopathy
نویسندگان
چکیده
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) are a group of systemic autoimmune disorders characterized by necrotizing inflammation of medium-tosmall vessels, a relative paucity of immune deposits, and an association with detectable circulating ANCAs. AAVs include granulomatosis with polyangiitis (renamed from Wegener’s granulomatosis), microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis Received: September 29, 2016 Accepted: October 26, 2016 Published online: December 13, 2016 Maik Gollasch, MD, PhD Experimental and Clinical Research Center Charité – Universitätsmedizin Berlin, Lindenberger Weg 80 DE–13125 Berlin (Germany) E-Mail maik.gollasch @ charite.de www.karger.com/bmh This article is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes as well as any distribution of modified material requires written permission.
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